Table 1.
Group: | Lowlanders | Highlanders | P values | |||
---|---|---|---|---|---|---|
Subgroup: | Controls (n = 17) | CMS− (n = 14) | CMS+ (n = 23) | CMS− vs. controls | CMS+ vs. controls | CMS+ vs. CMS− |
Clinical | ||||||
Age (years) | 56 ± 18 | 52 ± 12 | 56 ± 11 | 0.614 (between groups) | ||
Hb (g/dL) | 15.0 ± 1.3 | 17.2 ± 1.1* | 20.9 ± 1.7*† | <0.001 | <0.001 | <0.001 |
Hct (%) | 46 ± 4 | 52 ± 4* | 63 ± 6*† | 0.002 | <0.001 | <0.001 |
(%) | 97 ± 0 | 91 ± 5* | 88 ± 4*† | <0.001 | <0.001 | 0.044 |
caO2 (mg/dL) | 20.2 ± 1.8 | 21.6 ± 1.8 | 25.5 ± 2.3 | 0.147 | <0.001 | <0.001 |
CMS score (points) | 0 ± 0 | 2 ± 2 | 8 ± 5*† | 0.369 | <0.001 | <0.001 |
Anthropometrics | ||||||
Body mass (kg) | 82.0 ± 13.4 | 71.6 ± 8.9 | 78.2 ± 11.8 | 0.053 (between groups) | ||
Stature (m) | 1.77 ± 0.06 | 1.63 ± 0.04 | 1.62 ± 0.06 | <0.001 | <0.001 | 1.000 |
BMI (units) | 26 ± 4 | 27 ± 4 | 30 ± 4* | 1.000 | 0.025 | 0.122 |
Waist:hip | 0.93 ± 0.08 | 0.95 ± 0.05 | 0.99 ± 0.04* | 1.000 | 0.019 | 0.162 |
Education | ||||||
Secondary (n/%) | 16/94 | 13/93 | 20/87 | 0.697 (between groups) | ||
University (n/%) | 8/47 | 4/29 | 5/22 | 0.225 (between groups) |
Values are mean ± SD; CMS−/CMS+, highlanders without/with chronic mountain sickness; Hb, haemoglobin; Hct, haematocrit; , arterial oxyhaemoglobin saturation; caO2, arterial oxygen content; BMI, body mass index. *Different vs. lowlanders (P < 0.05); †different vs. CMS− (P < 0.05). Clinical and anthropometric data were analysed using one‐way ANOVAs and post hoc Bonferonni‐adjusted independent samples t‐tests. Education data were analysed using Pearson chi‐square tests.