[18F]-FDG PET/CT analysis of regional glucose uptake. (a) [18F]-FDG imaging protocol. (b) [18F]-FDG scans, representative MIP PET/CT images (upper panel), quantification by VOI analysis, cumulative average ratios of radiotracer uptake, HLI: n=12 (day 0); n=5 (d0.5), n=10 (d3), n=12 (d7) and n=2 (d10, d15, d20); sham: n=5 (d0.5), n=3 (d3) and n=6 (d7). * vs. baseline and # vs. sham, Kruskal-Wallis test. The color bar represents the color spectrum scaled to the middle VOI of the control leg and indicates the ischemic to non-ischemic ratio. (c) Combined analysis of radiotracer uptake in middle VOI from [99mTc]-Sestamibi, [99mTc]-HSA (see Figures 1c and 1e) and [18F]-FDG.