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. 2019 Jan 1;9(1):11–19. doi: 10.7150/thno.29740

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Representative ex vivo autoradiographic images (ARG) of brains from unblocked and blocked with 5 mg/kg nisoxetine adult (A) and immature (B) Sprague-Dawley rats 60 min after [¹⁸F]NS12137 injection at the level of the locus coeruleus (LC) and bed nucleus of the stria terminalis (BNST). White arrows indicate the location of the LC and black arrows indicate the location of BNST. (C) LC, BNST, neocortex (CTX), and striatum (STR) to cerebellum (CB) ratios calculated from the adult (Ad) and immature (Im) ARG brain image values (mean ± standard deviation).