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. 2018 Nov 29;597(2):431–447. doi: 10.1113/JP276106

Figure 8. Exendin‐4 regulates Cx36 levels on the cell membrane via both PKA and Epac2.

Figure 8

Quantification of Cx36 plaque area per number of nuclei (A) and number of Cx36 plaques per number of nuclei (B) in mouse islets treated with cytokines, 10 nM exendin‐4, the PKA activator 6‐Bnz, or the Epac2 activator 8‐Me as indicated for 24 h, normalized to control islets from each experiment (n = 3). Data represent means ± SEM. *Significant difference from control islets determined with 95% confidence intervals.