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. 2019 Jan 14;14:16. doi: 10.1186/s13023-018-0976-2

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Incidence of Turner syndrome according to karyotype. Incidence of a all Turner syndrome (TS); b 45,X TS; and c TS with other karyotypes per million females during 1970–2014. Solid lines illustrate time trend in incidence during the 1970–2014. P-values indicate the significance level of time trend in incidence