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. 2019 Jan 14;19:22. doi: 10.1186/s12862-018-1326-7

Table 4.

False positive rates (null scenarios) and true positive rates (alternative scenarios) for three LRTs when the evolutionary process includes DT nucleotide substitutions between codons, ω variability among sites, and MNRs

SNR (eβHI = 1) High MNR (eβHI = 0.05)
ω 0 ω 1 ω 2 LRT-1 LRT-2 LRT-3 LRT-1 LRT-2 LRT-3
Null scenarios False positives
3a 0.05 1.0 1.0 0.55 0.02 0.03 0.0 0.06* 0.10*
Alternative scenarios True positives
3b 0.05 0.5 2.0 0.95 0.87 0.92 0.01 0.44 0.26
3c 0.05 1.0 2.0 0.99 0.47 0.46 0.0 0.27 0.18

LRT-1 compares M1a to M2a (under-fit models). LRT-2 compares G1ax to G2ax (perfect-fit models). LRT-3 compares G1a13 to G2a13 (over-fit models). The asterisk symbol (*) indicates that the results are based on < 100 replicates due to convergence problems with some datasets when there was high MNRs. For LRT-2 case 3a is based on 99 replicates. LRT-3 case 3a is based on 91 replicates