Table 4.
The association between percentage change of serum uric acid and incident diabetes.
| Percentage change of serum uric acid | Total | Diabetes (n, %) | RR (95% CI) | ||
|---|---|---|---|---|---|
| Model 1∗ | Model 2† | Model 3‡ | |||
| ≤ −10% | 4133 | 223 (5.40) | 0.81 (0.69-0.95) | 0.83 (0.71-0.99) | 0.84 (0.72-0.99) |
| > −10% and ≤10% | 7663 | 412 (5.38) | 1.00 | 1.00 | 1.00 |
| >10% and ≤30% | 2900 | 163 (5.62) | 1.40 (1.17-1.68) | 1.34 (1.12-1.60) | 1.30 (1.08-1.55) |
| >30% | 707 | 43 (6.08) | 2.00 (1.48-2.72) | 1.85 (1.37-2.50) | 1.71 (1.27-2.30) |
| P for trend | <0.0001 | <0.0001 | <0.0001 | ||
Data were relative risks (RRs) and 95% confidence intervals (CIs). ∗Adjusted for age, sex, and serum uric acid at baseline. †Adjusted for variables in model 1 as well as education level, smoking, alcohol consumption, physical activity, family history of diabetes, and body mass index at baseline. ‡Adjusted for variables in model 2 as well as systolic blood pressure, diastolic blood pressure, total cholesterol, triglycerides, and high-density lipoprotein cholesterol at baseline.