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. 2019 Jan 8;10:425. doi: 10.3389/fnagi.2018.00425

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Copyright © 2019 Bouter, Henniges, Franke, Irwin, Sahlmann, Sichler, Beindorff, Bayer and Bouter.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Image analysis using a mouse brain atlas. (A–C) Illustration of brain regions that are ascertained by the mouse brain atlas in sagittal view. Lines indicate the level of coronal slices shown in (D–O). Magnetic resonance imaging (MRI) images (D–F) were used to match volumes of interest (VOIs) of the mouse brain atlas to individual brains of each mouse. (G–I) Examples of predefined VOIs matching the MRI in coronal view. Positron-emission tomography (PET) images were fused to the MRI (J–L) in order to match VOIs to the PET images (M–O). A, Amygdala; Bs, Brain Stem; C, Cortex; Cb, Cerebellum; H, Hypothalamus; Hc, Hippocampus; M, Midbrain; O, Olfactory Bulb; S, Septum/Basal Forebrain; St, Striatum; T, Thalamus.