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Increased microgliosis and astrogliosis in Tg4–42 mice. (A,B,E) Tg4–42 mice displayed significantly more reactive microglia activity in the brain compared to age-matched WT controls. (C,D,F) Tg4–42 mice exhibited ~20% more astroglia reactivity than WT controls. Scale bar: (D) = 200 μm. Unpaired t-test; **p < 0.01; *p < 0.05; data presented as mean ± SEM.
