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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: Exp Neurol. 2018 Apr 10;306:122–131. doi: 10.1016/j.expneurol.2018.04.005

Fig. 3.

Fig. 3.

Endogenous recovery is not sufficient to mediate functional activity through the contused bulbospinal pathways at both acute and chronic time points post injury. EMG data is shown for the diaphragm (dia), external intercostals (elC) and genio-glossus (genio) ipsilateral to the A) sham or B) contusion injury i) 3 days and ii) 12 weeks after C3 contusion. While recovery in ipsilateral diaphragm activity following contusion (Cx) is evident at chronic stages it is not sufficient to maintain that activity when ipsilateral pathways are isolated through right contralateral hemisection (Hx; dashed line), regardless of time post injury. This effect is evident in all inspiratory muscles. All panels are recorded in the same animal.