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. 2018 Oct 10;10(1):118–133. doi: 10.1039/c8sc03530j

Table 1. Additional peptides synthesised in this study (all synthesised as CoA thioesters, yield indicating conversion of pure hydrazide to CoA conjugate, purity of all peptides > 90%).

Compound Sequence Yield [mg] Yield [%]
2 d-Hpg/d-Tyr/l-Hpg/d-Hpg/d-Hpg/l-Phe 0.78 mg 12%
3 d-Hpg/d-Tyr/l-Hpg/d-Hpg/d-Hpg/l-4-cyano-Phe 0.54 mg 10%
5 d-Hpg/d-Cl-Tyr/l-Hpg/d-Hpg/d-Hpg/l-Cl-Tyr 0.20 mg 7%
6 d-Hpg/d-Cl-Tyr/l-Phe/d-Hpg/d-Hpg/l-Cl-Tyr 1.2 mg 8%
D-1 d-Hpg/d-Tyr/l-Hpg/d-Hpg/d-Hpg/d-Tyr 0.73 mg 9%
D-4 d-Hpg/d-Tyr/l-Phe/d-Hpg/d-Hpg/d-Tyr 2.9 mg 43%
7 d-Hpg/d-Tyr/l-Hpg/d-Hpg/d-Hpg 1.0 mg 9%
8 d-Hpg/d-Tyr/l-Phe/d-Hpg/d-Hpg 3.7 mg 34%
9 d-Hpg/d-Cl-Tyr/l-Phe/d-Hpg/d-Hpg 3.3 mg 60%