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. 2019 Jan 15;14(1):e0209593. doi: 10.1371/journal.pone.0209593

Table 1. Baseline characteristics of the study population.

Years 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 ptrend
Total AF patients 124549 137604 150301 163943 177663 185205 205813 225834 248925 276842 <0.001
AF patients with PCI 2140 (1.7) 2446 (1.8) 2511 (1.7) 2553 (1.6) 2778 (1.6) 2713 (1.5) 2940 (1.4) 3157 (1.4) 3411 (1.4) 3631 (1.3) <0.001
Total PCI procedure 2541 2933 2985 3026 3248 3200 3443 3694 3932 4220 <0.001
Number of PCI per patient 1.19±0.42 1.20±0.43 1.19±0.41 1.19±0.41 1.17±0.39 1.18±0.40 1.17±0.39 1.17±0.39 1.15±0.37 1.16±0.40 <0.001
Demographics
Age, years 66.3±10.5 67.1±10.3 67.6±10.4 68.9±10.0 69.0±10.2 70.1±9.8 70.2±10.3 70.1±10.4 70.5±10.8 70.8±10.5 <0.001
Age
    65–74 years 839 (39.2) 974 (39.8) 1023 (40.7) 1047 (41.0) 1097 (39.5) 1050 (38.7) 1079 (36.7) 1122 (35.5) 1124 (33.0) 1187 (32.7)
    75 years ≤ 472 (22.1) 589 (24.1) 672 (26.8) 790 (30.9) 878 (31.6) 988 (36.4) 1120 (38.1) 1174 (37.2) 1376 (40.3) 1501 (41.3)
Male 1403 (65.6) 1578 (64.5) 1595 (63.5) 1646 (64.5) 1802 (64.9) 1782 (65.7) 1918 (65.2) 2078 (65.8) 2277 (66.8) 2457 (67.7) <0.001
Comorbidities
Diabetes mellitus 740 (34.6) 850 (34.8) 881 (35.1) 944 (37.0) 1015 (36.5) 1038 (38.3) 1136 (38.6) 1242 (39.3) 1289 (37.8) 1463 (40.3) <0.001
Hypertension 1984 (92.7) 2239 (91.5) 2296 (91.4) 2297 (90.0) 2457 (88.4) 2364 (87.1) 2566 (87.3) 2779 (88.0) 2951 (86.5) 3098 (85.3) 0.012
Dyslipidemia 1776 (83.0) 2030 (83.0) 2040 (81.2) 2060 (80.7) 2215 (79.7) 2151 (79.3) 2429 (82.6) 2606 (82.6) 2958 (86.7) 3121 (86.0) <0.001
Congestive heart failure 679 (31.7) 690 (28.2) 791 (31.5) 876 (34.3) 1094 (39.4) 1259 (46.4) 1401 (47.7) 1617 (51.2) 1900 (55.7) 2118 (58.3) <0.001
Myocardial infarction 1207 (56.4) 1287 (52.6) 1209 (48.2) 1201 (47.0) 1242 (44.7) 1079 (39.8) 1194 (40.6) 1330 (42.1) 1491 (43.7) 1625 (44.8) <0.001
Peripheral arterial disease 509 (23.8) 518 (21.2) 637 (25.3) 694 (27.2) 664 (23.9) 641 (23.6) 691 (23.5) 726 (23.0) 784 (23.0) 884 (24.4) <0.001
Stroke/TIA/thromboembolism 613 (28.6) 736 (30.1) 685 (27.3) 710 (27.8) 799 (28.8) 820 (30.2) 912 (31.0) 927 (29.4) 993 (29.1) 1071 (29.5) <0.001
Intracranial hemorrhage 53 (2.5) 48 (2.0) 57 (2.3) 66 (2.6) 86 (3.1) 80 (3.0) 89 (3.0) 134 (4.2) 132 (3.9) 97 (2.7) <0.001
CHA2DS2-VASc Score 4.3±1.8 4.3±1.8 4.3±1.8 4.5±1.8 4.4±1.9 4.6±1.9 4.7±1.9 4.7±1.9 4.8±1.9 4.8±1.9 <0.001
    Score 2 ≤ 2058 (96.2) 2345 (95.9) 2410 (96.0) 2458 (96.3) 2646 (95.3) 2604 (96.0) 2851 (97.0) 3063 (97.0) 3294 (96.6) 3528 (97.1) <0.001

Abbreviations: AF, atrial fibrillation; PCI, percutaneous coronary intervention; TIA, transient ischemic attack

Values are given as mean±standard deviation or number (percentage), unless otherwise indicated.