Table 4. Prediction of lymph node metastases in 495 patients with endometrial cancer, univariate and multivariate logistic regression.

Variable	N	Univariate OR	95% CI	P	Multivariate OR	95% CI	P
Curretage histology				0.014			0.036
Low risk*	373
High risk**	122	2.06	1.16–3.66		1.87	1.04–3.37
GDF-15				0.001			0.001
Low	346
High tertile	149	2.64	1.52–4.61		2.49	1.42–4.37

Variables significant in univariate analyses were used in the final multivariate model.

*Low-risk patients defined as endometrioid histology and grade 1 or grade 2 disease on preoperative curettage.

**High-risk patients defined as endometrioid histology and grade 3 disease or non-endometrioid histology on preoperative curettage.