Figure 1.

(A) MDSC expression in S. aureus biofilm exposure. The bar graph (left panel) was illustrated and converted based on the flow cytometry results (right panel). (B) CURN suppressed biofilm-induced MDSC expansion in a dose-dependent manner. (C) CUR dissolved in PBS did not affect MDSC expansion. Data are expressed as the mean ± SD, *P<0.05 compared to biofilm-untreated group in (A). *P<0.05 and **P<0.01 compared to the biofilm-induced but no CURN treated group.

Abbreviations: CUR, curcumin; CURN, CUR nanoparticles; MDSCs, myeloid-derived suppressor cells; S. aureus, Staphylococcus aureus.