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. 2018 Dec 6;53(1):463–474. doi: 10.1021/acs.est.8b04281

Figure 4.

Figure 4

Gene set enrichment for KEGG pathways in heart tissues from 5 and 15 day old larval zebrafish in BPA and MBP exposure treatments (versus solvent controls). Sequence data were generated from hearts pooled from ∼30 individuals from each of four separate aquaria (nominally n = 4 experimental replicates) per exposure treatment. Enriched pathways were identified using Enrichr and referenced to the KEGG database (2016). Pathways highlighted in red boxes are calcific aortic valve disease (CAVD) biomarkers. Also see enriched Reactome pathways (in SI Figure S8).