Figure 3.
Malat1 is dispensable for TFH differentiation. (a-b) Flow cytometry analysis of CD4+ T cell pool at 8 days after infection. The percentage (left) and number (right) of effector CD4+ T cells are shown in b. (c) Flow cytometry analysis of SLAM− CXCR5+ TFH cells (top), PD-1hiCXCR5+ GC TFH cells (middle), and Bcl-6hiCXCR5+ GC TFH cells (bottom) at day 8 after LCMV infection. (d-e) The percentages (d) and numbers (e) of TFH cells in c. (f) Analysis of GC B cells (top) and plasma cells (bottom) in spleen by flow cytometry. (g) The percentages (left) and numbers (right) of GC B and plasma cells in f. (h) Analysis of LCMV-specific IgG (left) and IgM (right) in the sera after LCMV infection. Data represent mean ± s.d.