Table 1. Brief overview of breast cancer cell line-derived xenograft (CDX), patient-derived xenograft (PDX) and syngeneic mouse models.

		Implantation site	Mice strain	Cell line	Subtype	ER	PR	HER2	References
CDX model	subcutaneous CDX	Subcutaneous	BALB/c, Nude	MDA-MB-231	Basal	−	−	−	[18]
				MDA-MB-435	Basal	−	−	−	[54]
				BT-474	Luminal B	+	+	+	[55]
	Orthotopic CDX	Mammary fat pad	NOD/SCID	MDA-MB-231	Basal	−	−	−	[22]
				MDA-MB-435	Basal	−	−		[23]
				SUM1315	Basal	−	−		[24]
				MCF7	Luminal A	+	+		[25]
				T47D	Luminal A	+	+		[26]
	Metastatic CDX	Tail vein	NOD/SCID	MDA-MB-231	Basal	−	−	−	[56]
				SUM149	Basal	−	−		[57]
PDX model		Subcutaneous	BALB/c, Nude						[58]
		Mammary fat pad	NOD/SCID						[59]
		Mammary fat pad	NSG						[60]
		Humanized Mammary fat pad	NOD/SCID						[61]
Syngeneic model		Mammary fat pad	BALB/c	4T1		-	-	-	[38]