Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jan 9;9:3301. doi: 10.3389/fmicb.2018.03301

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Singh, Adams and Brown.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Schematic representation of capsule polysaccharide assembly and export in A. baumannii. Synthesis begins with the initial transferase (Itr; maroon) located in the inner membrane (IM) transferring the first sugar of the repeating unit to a lipid carrier (Und-P; green circle). Subsequent sugars are then added to the growing unit by specific glycosyltransferases (Gtr; yellow) on the cytosolic side of the inner membrane. The capsule subunit (K unit) is then transferred to the periplasm via the integral membrane protein Wzx (dark blue). The sugar subunits are polymerized by the Wzy protein (purple) and the Wza/Wzb/Wzc complex (cyan, lime, red) coordinates high level polymerization and export of the growing chain, moving them to the outer membrane (OM). For glycosylation, PglL (orange) links the K units onto selected outer membrane proteins (OMP; dark green).