Table 2.

Serum GDF15 levels before and after thionamide treatment in hyperthyroid subjects.

	Before	After	P-value
N	43	43
Weight (kg)	52.23 ± 6.26	57.00 ± 7.33	<0.01
ALT (U/L)	37.81 ± 15.92	20.98 ± 9.32	<0.001
AST (U/L)	30.98 ± 12.28	20.63 ± 6.81	<0.001
TBIL (mmol/L)	14.66 ± 7.47	12.08 ± 4.32	0.053
DBIL (mmol/L)	4.88 ± 3.25	3.56 ± 1.61	0.019
FINS (mm/L)	10.69 ± 13.1	8.85 ± 6.81	0.416
FPG (mM)	5.14 ± 0.76	5.01 ± 0.44	0.335
TG (mM)	0.99 ± 0.68	1.11 ± 0.62	0.392
TC (mM)	3.66 ± 0.87	5.50 ± 1.01	<0.001
HDL-c (mM)	1.37 ± 0.39	1.66 ± 0.32	<0.001
Free T3 (pM)	26.62 ± 19.40	4.53 ± 0.83	<0.001
Free T4 (pM)	66.24 ± 32.78	13.05 ± 2.63	<0.001
TSH (mIU/L)	0.011 ± 0.016	0.86 ± 1.28	<0.001
GDF15 (pmol/L)	293.27 ± 119.49	118.10 ± 71.83	<0.001

Data are presented as means ± standard deviation (SD).