Table 3.
ORs for association between serum GDF15 levels and hyperthyroidism with the use of three logistic regression models.
| Variable | OR (95% CI) | P-value |
|---|---|---|
| MODEL 1 | ||
| GDF15a | 6.652 (4.184–11.353) | <0.001 |
| MODEL 2 | ||
| Age | 1.019 (0.946–1.098) | 0.622 |
| Gender (female vs. male) | 0.517 (0.230–1.161) | 0.110 |
| BMI | 0.533 (0.424–0.668) | <0.001 |
| GDF15a | 8.225 (4.805–15.380) | <0.001 |
| MODEL 3 | ||
| Age | 0.903 (0.769– 1.060) | 0.214 |
| Gender (female vs. male) | 0.249 (0.050–1.236) | 0.089 |
| BMI | 0.420 (0.256–0.691) | 0.0006 |
| ALT | 1.299 (1.127–1.498) | 0.0003 |
| AST | 1.080 (0.995–1.173) | 0.065 |
| FPG | 6.416 (0.848–48.567) | 0.072 |
| TC | 0.030 (0.006–0.140) | <0.001 |
| GDF15a | 13.193 (4.754–55.090) | <0.001 |
a
OR and 95% CI expressed as per SD increase of GDF15.