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. 2019 Jan 9;9:710. doi: 10.3389/fgene.2018.00710

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Copyright © 2019 Costa, Sobkowiak, Parreira, Edgeworth, Viveiros, Clark and Couto.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Maximum likelihood phylogeny of the norA sequences analyzed in this study. Identical norA sequences among all samples used in this study have been collapsed and represented by a single label, which denotes a representative ST/CC of that group. The number of sequences is denoted by the last number of the tip label. Four major groups are found, clustering with the norA alleles described in literature, norAI (D90119.1), norAII (AB019536.1), norAIII (M97169.1), and the allelic variant norA-CC59/121. The norAI associated group is the most diverse, including samples belonging to CC1, CC5, CC8, CC15, CC80, and a wide range of sequence types. The norAII associated group contains samples belonging to clonal complexes CC22, CC30, CC36, and CC398. Major nodes supported with bootstrap values above 75% are denoted with a star.