FIGURE 4.

Effect of 6-OHDA injection, on the 7th, 21st, 35th and day of the experimental protocol, in motor parameter evaluated in the rotarod test d. (A–C) Latency to fall in seconds at speeds of 12, 20, and 24 revolutions per minute (rpm) at the 7th, (D–F) 21st, and (G–I) 35th day. Data are median and interquartile range as they are asymmetrically distributed (non-parametric) in (A–F), and mean ± SD in (G–I). ^∗ and ^# Indicates a significant difference compared to the Control and Dexa groups, respectively, using unpaired Mann–Whitney in (A–F), and ordinary two-way ANOVA with Tukey’s post hoc test in (G–I). n = 16–17 in (A–F), and 8–9 in (G–I), p < 0.05.