Table 1.
Patient groupa | Sex (f/m) | Age (years) | Symptom duration (years)b | Follow-up duration (years)c | Education (years)d | MMSE scoree | Consistency with AUC (yes/no) | Hippocampal atrophy (yes/no)f |
---|---|---|---|---|---|---|---|---|
All | 41/43 | 66.9 (8.2) | 2.7 (2.2) | 2.5 (1.4) | 13.5 (3.4) | 22.3 (4.6) | 69/15 | 13/44 |
AD | 19/22 | 65.8 (7.5) | 2.7 (2.1) | 2.8 (1.3) | 13.8 (3.7) | 21.2 (4.5)g | 27/14 | 8/16 |
Non-ADh | 22/21 | 67.9 (8.8) | 2.8 (2.3) | 2.2 (1.4) | 13.2 (3.1) | 23.5 (4.4) | 41/1 | 5/28 |
Data are given as mean values (standard deviation)
AD Alzheimer’s disease, MMSE Mini-Mental State Examination, AUC Appropriate Use Criteria
aAccording to baseline clinical diagnosis
bBefore PET
cAfter PET
dAvailable in 73 patients
eAvailable in 79 patients. The MMSE score at the time of PET was not properly archived in five patients
fHippocampal atrophy indicated on MRI in those patients who underwent MRI at baseline
gMMSE scores were 20.5 ± 4.2 in patients with early-onset AD and 21.8 ± 4.7 in those with late-onset AD (p = 0.354, t test), and 22.9 ± 4.6 in patients with early-onset non-AD and 23.8 ± 4.4 in those with late-onset non-AD (p = 0.558, t test)
hMajor neurocognitive disorder due to non-AD aetiology