Table 1.
Crude drug composition of CLM.
| Plant name | Composition (g) | Major components |
|---|---|---|
| Bupleuri radix | 6 | Saikosaponin a, c, d, e |
| Fossilia ossis mastoid | 2.25 | Calcium base |
| Scutellariae radix | 2.25 | Baicalin, Wogonin |
| Zingiberis rhizoma | 2.25 | Gingerol, Shogaol |
| Ginseng radix | 2.25 | Ginsenoside |
| Cinnamomi cortex | 2.25 | Cinnamic aldehyde |
| Hoelen | 2.25 | Eburicoic acid |
| Pinelliae tuber | 3 | Homogenistic acid |
| Radix et Rhizoma Rhei | 3 | Anthraquinone |
| Ostreae testa | 2.25 | Calcium base |
| Zizyphi fructus | 3 | Zizyphus saponin, betulinic acid |
These 11 dried herbal and mineral drugs were soaked in water for 30 min, and then were decocted two times with boiling water in the ratio of 1: 8 for 2 h. After collecting all the solution, placed in a water bath at 60°C and evaporated to a target concentration for frozen storage. The yield of the preparation was about 42%. The concentration of the solutions for administration was diluted to 210 mg/ml.