Table 1.

Demographic details and task performance

	BDNF discovery sample			BDNF replication sample			Schizophrenia relatives study
	Val-carriers (n = 50)	Met-carriers (n = 35)	p-Value	Val-carriers (n = 166)	Met-carriers (n = 87)	p-Value	Relatives (n = 58)	Controls (n = 180)	p-Value
Demographic information
Age (year), mean ± SD	24.24 ± 4.12	26.11 ± 7.32	0.136	33.46 ± 9.43	34.32 ± 10.24	0.502	32.34 ± 12.25	33.16 ± 9.75	0.647
Sex (males/females), mean ± SD	13/37	19/16	0.012	77/89	35/52	0.355	23/35	69/111	0.878
Site (Mannheim/Berlin/Bonn)	50/0/0	35/0/0	N.A.	40/52/74	27/17/43	0.120	21/19/18	51/61/68	0.480
School years, mean ± SD	≥12	≥12	N.A.	15.41 ± 2,54	15.45 ± 2.53	0.930	15.03 ± 2.71	15.24 ± 2.55	0.602
fMRI task performance
Incongruent trials, accuracy (%), mean ± SD	97.25 ± 4.80	97.79 ± 3.20	0.566	97.29 ± 5.54	96.38 ± 10.45	0.366	96.98 ± 4.63	97.18 ± 7.53	0.850
Congruent trials, accuracy (%), mean ± SD	98.50 ± 4.87	98.86 ± 2.45	0.691	99.32 ± 3.01	98.60 ± 4.25	0.161	99.45 ± 1.83	99.57 ± 1.52	0.601
Neutral trials, accuracy (%), mean ± SD	99.19 ± 2.59	99.11 ± 1.93	0.884	98.95 ± 3.78	98.59 ± 4.50	0.502	99.28 ± 1.71	99.23 ± 2.96	0.909
No-go trials, accuracy (%), mean ± SD	92.52 ± 5.98	94.48 ± 4.74	0.109	91.13 ± 6.87	91.68 ± 6.78	0.546	90.75 ± 7.79	90.90 ± 7.08	0.886
Incongruent trials, RT (ms), mean ± SD	616.38 ± 122	607.44 ± 99	0.721	625.59 ± 94	653.12 ± 140	0.101	634.76 ± 129	633.43 ± 106	0.937
Congruent trials, RT (ms), mean ± SD	563.62 ± 126	555.45 ± 94	0.746	571.90 ± 96	593.64 ± 129	0.169	570.82 ± 106	576.21 ± 98	0.722
Neutral trials, RT (ms), mean ± SD	589.90 ± 129	588.03 ± 106	0.944	603.38 ± 97	622.53 ± 127	0.220	608.80 ± 114	606.01 ± 97	0.867

Among the discovery sample, all participants possessed university entrance qualifications equivalent to 12 years of schooling. Data on further education were not available

Ms milliseconds, SD standard deviation