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. 2018 Nov 13;294(2):716–725. doi: 10.1074/jbc.RA118.006134

Figure 1.

Figure 1.

EPSPS reaction. The reaction is an addition/elimination in which an enzymic base deprotonates the 5-hydroxyl of S3P, allowing the electron pair to attack the oxocarbenium ion of PEP (shown to suggest the species mimicked by glyphosate), generated by the enzyme.