Table 1.

Mean physiologic parameters measured at 5 different intervals of steady-state plasma glucose concentration in MRS experiments.

Plasma glucose range (mM)		<8	8–14	14–20	20–26	>26
Body Temperature (°C)	Control	37.5 ± 0.2	37.4 ± 0.1	37.5 ± 0.1	37.2 ± 0.2	37.3 ± 0.1
	Caffeine	37.5 ± 0.2	37.2 ± 0.2	37.3 ± 0.1	37.1 ± 0.1	37.4 ± 0.1
	GK	37.0 ± 0.1	37.3 ± 0.2	37.2 ± 0.3	37.4 ± 0.2	37.0 ± 0.1
	GK + Caffeine	37.5 ± 0.1	37.3 ± 0.2	37.5 ± 0.2	37.6 ± 0.1	37.2 ± 0.1
Arterial pH	Control	7.34 ± 0.01	7.34 ± 0.01	7.34 ± 0.01	7.31 ± 0.02	7.33 ± 0.03
	Caffeine	7.42 ± 0.02	7.38 ± 0.01	7.35 ± 0.01	7.35 ± 0.01	7.33 ± 0.02
	GK	7.41 ± 0.02	7.40 ± 0.02	7.42 ± 0.02	7.40 ± 0.01	7.39 ± 0.01
	GK + Caffeine	7.44 ± 0.01	7.45 ± 0.01	7.39 ± 0.02	7.39 ± 0.02	7.38 ± 0.02
PaCO2 (mm Hg)	Control	44.7 ± 2.0	44.7 ± 1.6	46.8 ± 1.3	44.9 ± 1.9	42.1 ± 2.0
	Caffeine	39.9 ± 2.9	41.5 ± 2.7	45.7 ± 3.9	41.7 ± 2.7	41.4 ± 2.9
	GK	39.0 ± 3.4	38.6 ± 2.0	37.2 ± 2.7	40.3 ± 2.6	43.2 ± 2.3
	GK + Caffeine	35.7 ± 1.7	39.5 ± 4.7	38.9 ± 3.0	40.7 ± 3.0	40.1 ± 1.3

Data is mean ± SEM of 6 to 8 rats in each experimental group.