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. 2019 Jan 9;9:3317. doi: 10.3389/fmicb.2018.03317

FIGURE 5.

FIGURE 5

A subset of pyoverdine inhibitors behave as anti-virulents. (A) MICs, effective concentrations (EC, defined as the minimum concentration required for statistically significant amelioration of killing), and the ratios of MIC to EC are shown for a panel of classical antimicrobials, the antivirulents LK11, LK31, and LK31a, and the bifunctional compounds LK10 and LK12. (B,C) Colony-forming unit counts for P. aeruginosa grown in the presence of DMSO or 100 μM of LK11, LK31, and LK31a in nutrient-poor SK media (B) or more nutritious M9 media (C). At least three biological replicates were performed for each experiment.