Fig. 6.

mPFC projections to the BLA play a role in the ketamine response. a Viral strategy and representative mCherry and hM4Di expression (red = mCherry, hM4D1, cyan = DAPI). b FST immobility time 24 h after CNO and ketamine administration (factoral ANOVA interaction p < 0.05, post-hoc t-test *p < 0.05). c Time to feed in the NSF test 24 h after CNO and ketamine administration (Mantel–Cox (log rank) overall p = 0.06); n = 9 mCherry Veh, hM4Di Veh, hM4Di Ket, n = 10 mCherry Ket. All male. Error bars represent mean ± SEM, scale bar 100 µM