Table 2.

Guidelines on screening for hepatitis B virus markers before immunosuppression or chemotherapy

Society	Who should be screened?	Screening tests
AGA	Patients at moderate or high risk of HBVr	HBsAg, anti-HBc + HBV DNA in case of positive results
ASCO	Groups at heightened risk for chronic HBV infection or if highly immunosuppressive treatment is planned	HBsAg+- anti-HBc in some populations
CDC	All persons receiving cytotoxic or immunosuppressive therapy	HBsAg, anti-HBc, and anti-HBs
DGHO	Groups at heightened risk	HBsAg, anti-HBc + HBV DNA in case of positive results
ECCO	All IBD patients at diagnosis	HBsAg, anti-HBc, and anti-HBs + HBV DNA in case of positive results
EASL	All candidates for chemotherapy and immunosuppression	HBsAg, anti-HBc, and anti-HBs +HBV DNA in case of positive results

AGA = American Gastroenterological Association; anti-HBc = hepatitis B core antibody; anti-HBs = hepatitis B surface antibody; ASCO = American Society of Clinical Oncology; CDC = Centers for Disease Control and Prevention; DGHO = German Society for Haematology and Medical Oncology; EASL = European Association for the Study of the Liver; ECCO = European Crohn´s and Colitis Organisation; HBsAg = hepatitis B surface antigen; HBV = hepatitis B virus; HBV DNA = hepatitis B virus DNA; HBVr = hepatitis B reactivation; IBD = inflammatory bowel disease