Table 1.
Characteristics of sample, stratified by p.C282Y genotype (homozygotes, heterozygotes, and no p.C282Y mutations, sex and age
| Characteristics | Men | Women | |||||
|---|---|---|---|---|---|---|---|
| Homozygotes | Heterozygotes | No p.C282Y mutations* | Homozygotes | Heterozygotes | No p.C282Y mutations* | ||
| All ages (40-70 years): | |||||||
| No (%) | 1294 (0.6) | 29 536 (14.3) | 175 539 (85.1) | 1596 (0.65) | 34 908 (14.3) | 208 370 (85.1) | |
| Mean (SD) age (years) | 56.85 (8.18) | 57.01 (8.12) | 57.00 (8.11) | 56.94 (7.98) | 56.48 (7.97) | 56.61 (7.94) | |
| No (%) consuming alcohol daily† | 324 (25.1) | 7544 (25.6) | 46 342 (26.4) | 256 (16.0) | 5765 (16.5) | 35 191 (16.90) | |
| No (%) with haemochromatosis baseline diagnosis | 156 (12.1) | 56 (0.2) | 55 (0.03) | 54 (3.4) | 17 (0.05) | 16 (0.01) | |
| Older ages (60-70 years): | |||||||
| No (%) | 593 (0.6) | 13 599 (14.3) | 80 945 (85.1) | 719 (0.7) | 14 905 (14.1) | 90 214 (85.2) | |
| Mean (SD) age (years) | 64.19 (2.84) | 64.29 (2.85) | 64.25 (2.86) | 64.26 (2.82) | 64.02 (2.86) | 64.04 (2.84) | |
| No (%) consuming alcohol daily† | 173 (29.2) | 3962 (29.2) | 24 277 (30.0) | 125 (17.4) | 2696 (18.1) | 16 714 (18.5) | |
| No (%) with haemochromatosis baseline diagnosis | 81 (13.7) | 31 (0.2) | 35 (0.04) | 34 (4.7) | 7 (0.05) | 5 (0.01) | |
*
No p.C282Y mutations, irrespective of p.H63D status.
†
0.07% of participants with missing data were excluded.