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. 2018 Dec 20;6(6):234–244.

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Combined loss of Eaf2 and Ell2 induced murine prostatic intraepithelial neoplasia in the mouse model. A. Histology of mouse ventral prostate from wild-type (Eaf2^+/+Ell2^+/+PbsnCre4), Eaf2^+/- (Eaf2^+/-Ell2^+/+PbsnCre4), Ell2-cko (Eaf2^+/+Ell2^-/-PbsnCre4), and Eaf2^+/-Ell2^+/- (Eaf2^+/-Ell2^loxp/+PbsnCre4) C57BL/6J male mice aged 24 months stained with hematoxylin and eosin (H&E). Original magnification, × 10, inset, × 40. B. Quantification of mPIN incidence in mice. Data are expressed as percentage from 3 to 6 mice per group. *P < 0.05.