Table 1.
Cohort characteristics
| Variable | Value |
|---|---|
| n | 342 |
| Age (y) | 63 (50‐75) |
| Female | 134 (39%) |
| Ethnicity | |
| White | 242 (71%) |
| South Asian | 62 (18%) |
| Black | 35 (10%) |
| Other | 3 (1%) |
| Aetiology of renal disease | |
| Ischaemic/hypertensive | 70 (20%) |
| Glomerulonephritis | 70 (20%) |
| Polycystic | 32 (9%) |
| Diabetic | 31 (9%) |
| Obstructive/reflux | 24 (7%) |
| Interstitial disease | 19 (6%) |
| Not known and other | 85 (25%) |
| No renal disease | 11 (3%) |
| eGFR (mL/min/1.73 m2) | 28 (18‐43) |
| Urine ACR (mg/mmol) | 35.5 (5.4‐120.6) |
| Diabetes | 122 (36%) |
| HbA1c (mmol/mol) | 42 (38‐50) |
| C‐reactive protein (mcg/mL) | 2.7 (1.2‐6.3) |
| Urine (THF+5αTHF)/THE | 1.23 (0.86‐1.80) |
Continuous variables are reported as median (interquartile range) and categorical variables as frequency (percentage).
ACR, albumin‐creatinine ratio; eGFR, estimated glomerular filtration rate; (THF+5αTHF)/THE, tetrahydrocortisol+5α‐tetrahydrocortisol/tetrahydrocortisone.