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QPCR analysis following APAP treatment. Control and Txnrd1ΔLiv mice (n = 3) were treated or untreated with a hepatotoxic dose of APAP for 6 h and mRNA levels determined for (A) enzymes involved in glutathione metabolism (Gstal, Gsta2, Gclc, Gsr, and Gss), (B) Cyp2e1, and (C) the transporters Abcc3 and Abcc4. *P < 0.05.
