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. Author manuscript; available in PMC: 2019 Jan 16.
Published in final edited form as: J Proteome Res. 2015 Mar 10;14(4):1937–1946. doi: 10.1021/pr5013152

Figure 5.

Figure 5.

Nutmeg inhibits colon tumorigenesis. (A) Tumor number (tumor diameter > 1 mm) in the colon of Apcmin/+ mice after nutmeg treatment for 4 months. (B) Size of colon tumors in Apcmin/+ mice after nutmeg treatment for 4 months. (C) PLS-DA model of serum samples from nutmeg-fed Apcmin/+ mice (n = 5, blue), vehicle-fed Apcmin/+ mice (n = 4, green), nutmeg-fed WT mice (n = 5, yellow), and vehicle-fed WT mice (n = 5, red). (D) Loading scatter plot of the PLS-DA model. Metabolite codes correspond to those in Table 1. All data were obtained in negative mode (ESI−) by UPLC−ESI− QTOFMS. Statistical analysis was performed using two-tailed Student’s t test and ANOVA (n = 4/5 in each group). *, P < 0.05 compared to vehicle-fed Apcmin/+ mice.