Table 1.
Demographic and clinical characteristics at index date, by screening period
| Characteristic | Pre-screening perioda n (%) or median (IQR) |
Post-screening periodb n (%) or median (IQR) |
p-value |
|---|---|---|---|
| N | 3215 (33) | 6404 (67) | |
| Age, years | 40 (34–46) | 44 (34–52) | < 0.0001 |
| Male sex | 2759 (86) | 5330 (83) | < 0.0001 |
| African American | 865 (27) | 2375 (37) | < 0.0001 |
| Hispanic ethnicity | 615 (19) | 1546 (24) | < 0.0001 |
| Men who have sex with men | 1969 (61) | 3045 (48) | < 0.0001 |
| Antiretroviral therapy naïve | 1188 (37) | 2752 (43) | < 0.0001 |
| HIV RNA, log10 copies/mL | 3.9 (2.2–4.8) | 2.0 (1.3–4.5) | < 0.0001 |
| HIV RNA < 50 copies/mL | 355 (11) | 2625 (41) | < 0.0001 |
| CD4 cell count | 274 (142–452) | 452 (270–660) | < 0.0001 |
| History of AIDS-defining event | 965 (30) | 959 (15) | < 0.0001 |
aPre-screening period: 01 January 1999 to 14 June 2008
bPost-screening period: 15 June 2008 to 31 July 2016