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. 2019 Jan 15;19:13. doi: 10.1186/s12871-019-0681-2

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — HPX up-regulated the expression of HO-1 on day 7 after focal cerebral I/R injury. When compared with the rats in the sham group, those with focal cerebral I/R injury exhibited an increase in the HO-1 protein expression on day 7 after I/R injury. The HO-1 protein expression was increased in the vehicle and MCAO group. HPX injection up-regulated the HO-1 expression. ^*P < 0.05 vs. sham group; ^#P < 0.05 vs. MCAO group; ^※P < 0.05 vs. vehicle group