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. 2019 Jan 15;38:20. doi: 10.1186/s13046-018-0995-9

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — MiR-214 suppressed the migration and invasion but not proliferation ability of GC cells. a Expression of miR-214 was significantly downregulated in CAFs than in paired NFs. b The ectopic expression of miR-214 in CAFs transfected with miR-214 mimics was confirmed by qRT-PCR. c, d and e The CCK8 and EdU assays showed that CAFs^miR-214-CM did not influence the proliferation of MGC-803 and SGC-7901 cells compared with CAFs^NC-CM (no significant difference, NS, P > 0.05). f and g CAFs^miR-214-CM markedly inhibited the migration and invasion of MGC-803 and SGC-7901 cells compared with CAFs^NC-CM (**P < 0.01)