Table 1.

Descriptions of intervention training session and control training session.

Training session schedule			Training session content and activity
Intervention training session for the training group (up to 2 hours)
	Introduction of SMRAa (10 min)		Content: introduction of what an SMRA is in general and what the Medisafe app is in particular (eg, who the developer is, where and at what cost and in which languages the app is available to use)
	Targeting TAMb variables (20 min)
		Perceived usefulness	Rationale for content: patients reported satisfaction with SMRA that visually (eg, medication pictures) supports correct medication taking [9]; patients described SMRA as useful as it reminds of and helps set up medication routines [19]
			Content: (to increase participants’ levels of perceived usefulness of SMRA) introduction of virtual pill box (ie, feature for visually keeping track of medication list) and reminder (ie, feature for being reminded of taking and refilling medications in a timely fashion) features of the Medisafe app
		Positive subjective norm	Rationale for content: patients’ perceptions of others who support patients’ medication adherence matter to patients’ continuous SMRA use [19]
			Content: (to increase participants’ levels of positive subjective norm regarding SMRA use) introduction of the Medfriend feature (ie, feature for notifying co-app users such as family members if a patient missed a reminder from the app so that they could call or text the patient to additionally remind of medication taking) of the Medisafe app
		Perceived ease of use (hands-on experience with SMRA)	Rationale for content: patients often struggled with navigating SMRA features by missing or misinterpreting app feature buttons [18]
			Content: provision of step-by-step instructions on how to use virtual pill box (eg, adding either prescribed or hypothetical medications to the app) and reminder (eg, scheduling reminders and receiving them from the app) features of the Medisafe app
			Activity: (to increase participants’ levels of perceived ease of SMRA use) participants practice the above features following step-by-step instructions; participants repeat the practice on their own to ensure their competency in app use
	Survey (10 min)		Activity: participants complete a survey measuring TAM variables
	Focus group (1 hour)		Activity: participants describe their perceptions of the Medisafe app in relation to TAM variables
Control training session for the nontraining group (up to 2 hours)
	Introduction of SMRA (10 min)		Content: introduction of what an SMRA is in general and what the Medisafe app is in particular
	Hands-on experience with SMRA (20 min)		Activity: participants explore any Medisafe app features on their own
	Survey (10 min)		Activity: participants complete a survey measuring TAM variables
	Focus group (1 hour)		Activity: participants describe their perceptions of the Medisafe app in relation to TAM variables

^aSMRA: smartphone medication reminder app.

^bTAM: technology acceptance model.