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Proposed kinetic mechanism for the Bm-iAANAT3-catalyzed N-acetylation of tryptamine. The thick lines in the scheme represent a preferred pathway in a random kinetic mechanism with acetyl-CoA binding first and N-acetyltryptamine being released last. A = Acetyl-CoA, B = tryptamine, P = CoA-SH, and Q = N-acetyltryptamine.
