Fig 3. Oral and subcutaneous flubendazole treatment reduces L. sigmodontis microfilariae in a dose and treatment duration dependent manner.
L. sigmodontis microfilariae counts per 10μl peripheral blood at 8 weeks post treatment end. Jirds received oral gavages of flubendazole once (40mg/kg) or for five or ten consecutive days at 2, 6 or 15mg/kg or subcutaneous flubendazole injections once with 2 or 10mg/kg or for five 5 days (10mg/kg). Shown are medians and the reduction of microfilariae levels in comparison to untreated jirds calculated from geometric means.
