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. 2019 Jan 16;14(1):e0209440. doi: 10.1371/journal.pone.0209440

Table 4. Unadjusted and age and sex adjusted proportions (with 95% CI) of deaths attributed to cardiovascular causes by eGFR strata.

Deaths attributed to
eGFR strata Ischaemic heart Disease Cerebrovascular disease Heart Failure Arrythmia Valvular disease Other CVD causes
>90 ml/min/1.73 m2
Unadjusted 47.5 (45.4 to 49.6) 23.0 (21.2 to 24.7) 6.3 (5.3 to 7.3) 2.1 (1.5 to 2.7) 1.4 (0.9 to 1.9) 19.7 (18.0 to 21.4)
Age/sex adjusted 41.6 (34.2 to 50.0) 27.3 (22.2 to 32.4) 8.9 (6.8 to 11.0) 2.8 (-13.7 to 19.4) 1.3 (0.8 to 1.9) 18.0 (14.5 to 21.6)
60–89 ml/min/1.73 m2
Unadjusted 37.6 (36.6 to 38.5) 23.3 (22.5 to 24.1) 11.8 (11.2 to 12.4) 7.5 (7.0 to 8.0) 2.5 (2.2 to 2.8) 17.3 (16.6 to 18.1)
Age/sex adjusted 38.1 (22.2 to 54.0) 23.4 (13.6 to 33.2) 11.3 (6.5 to 16.0) 7.0 (-32.0 to 46.0) 2.5 (1.4 to 3.6) 17.8 (10.3 to 25.1)
45–59 ml/min/1.73 m2
Unadjusted 39.2 (37.9 to 40.5) 19.5 (18.4 to 20.6) 13.2 (12.3 to 14.1) 9.4 (8.6 to 10.2) 3.4 (2.9 to 3.9) 15.3 (14.3 to 16.3)
Age/sex adjusted 40.7 (19.9 to 61.5) 19.3 (9.4 to 29.2) 12.2 (5.9 to 19.0) 8.5 (-38.4 to 55.5) 3.5 (1.7 to 5.4) 15.8 (7.7 to 23.8)
30–44 ml/min/1.73 m2
Unadjusted 39.8 (38.4 to 41.3) 16.7 (15.6 to 16.7) 15.1 (14.1 to 16.1) 8.5 (7.7 to 9.3) 4.4 (3.8 to 5.0) 15.5 (14.4 to 16.5)
Age/sex adjusted 41.3 (22.2 to 60.4) 16.5 (8.8 to 24.1) 14.0 (7.5 to 20.5) 7.7 (-35 to 50.5) 4.6 (2.4 to 6.7) 16.0 (8.5 to 23.4)
15–29 ml/min 1.73 m2
Unadjusted 44.2 (42.3 to 46.2) 11.9 (10.6 to 13.2) 18.3 (16.8 to 19.8) 7.2 (6.2 to 8.2) 4.0 (3.2 to 4.8) 14.4 (13.0 to 15.8)
Age/sex adjusted 45.7 (27.6 to 63.8) 11.8 (7.0 to 16.6) 17.1 (10.2 to 23.9) 6.6 (-30.5 to 43.7) 4.1 (2.3 to 5.9) 14.8 (8.8 to 20.1)
ESRD
Unadjusted 53.8 (50.1 to 57.5) 11.5 (9.2 to 13.9) 15.5 (12.8 to 18.2) 3.2 (1.9 to 4.5) 3.1 (1.8 to 4.4) 12.9 (10.4 to 15.4)
Age/sex adjusted 53.0 (42.3 to 63.6) 12.0 (8.6 to 15.4) 15.7 (11.6 to 19.8) 3.1 (-15.3 to 21.6) 3.1 (1.7 to 4.6) 13.1 (9.5 to 16.6)
Total (cases) 10201 5026 3285 1888 683 4,133

CVD, cardiovascular disease; eGFR, estimated glomerular filtration rate; ESRD, end-stage renal disease.