Skip to main content
. 2019 Jan 16;14(1):e0210253. doi: 10.1371/journal.pone.0210253

Table 2. Standardized incidence ratios by gender in each calendar period.

Gender Early cART era
(2000–2002)
Intermediate cART era
(2003–2005)
Late cART era
(2006–2009)

P value
2000–2002
vs.
2003–2005

P value
2006–2009
vs.
2003–2005
O/E SIR (95% CI) O/E SIR (95% CI) O/E SIR (95% CI)
Women 15/5.33 2.81 (1.58–4.64) 16/7.32 2.18 (1.25–3.55) 36/18.10 1.99 (1.39–2.75) 0.485 0.752
Men 132/97.10 1.35 (1.14–1.61) 205/117.96 1.74 (1.51–1.99) 259/230.80 1.12 (0.99–1.27) 0.028 <0.001
P value* 0.008 0.377 0.001

Abbreviations: CI, confidence interval; O/E, observed/expected cases; SIR, standardized incidence ratio.

P values for the SIRs were obtained by Poisson regression by comparison two by two and their 95% CIs were estimated with an exact method based on the Poisson distribution.

*P values for the SIRs were obtained by Poisson regression by comparison between men and women in each calendar period.