Effect of adiponectin (ApN) overexpression on body weight (A), systolic blood pressure (SBP; B), water intake (C), urine output (D), urinary albumin-creatinine ratio (A/C; E), and urinary albumin excretion (UAE; F) in mice with DOCA+ANG II-induced chronic kidney disease. WT, wild-type normal mice; WT/DOCA+ANG II, wild-type mice receiving DOCA+ANG II infusion; ApN-Tg/DOCA+ANG II, ApN transgenic mice receiving DOCA+ANG II infusion. *P < 0.05 vs. WT normal mice; #P < 0.05 vs. WT mice receiving DOCA+ANG II infusion.