Skip to main content
. 2018 Jun 6;315(3):F558–F571. doi: 10.1152/ajprenal.00137.2018

Fig. 5.

Fig. 5.

Effect of adiponectin (ApN) overexpression on glomerulosclerosis, tubular dilation, inflammation, and fibrosis and quantitative assessments of morphological damage in the kidneys of mice with DOCA+ANG II-induced chronic kidney disease. A and B: representative photomicrographs of glomeruli stained with periodic acid-Schiff (PAS) staining (A) and glomerular immunofluorescent staining for fibronectin (FN; B). Magnification ×400. C and D: representative photomicrographs of renal tubular dilation, inflammation, and tubulointerstitial fibrosis stained with PAS staining (C) and Masson’s trichrome (D). Magnification ×200. Graphic quantitative evaluations of glomerular matrix score and FN staining score and tubulointerstitial fibrosis are shown at right. ApN-Tg, ApN transgenic mice. *P < 0.05 vs. wild-type normal mice (WT); #P < 0.05 vs. wild-type mice receiving DOCA+ANG II infusion (WT/DOCA+ANG II).