Appendix 1—table 1. Global tractography fibre counts.

2 (pathway: SC-PUL, PUL-AMG)×2 (hemisphere: left, right) design. Four outliers removed out of 622.

Outliers removed	ANOVA main effects					t-tests for Simple Effects
	Effect	Df	F	P	ηp2	Df	T	P
	* Pathway	(3,4)	433.286	2.842 × 10−73*	0.413
	* Hemisphere	(3,4)	7.583	0.006 *	0.012
	* Pathway × Hemisphere	(1,616)	16.025	7.000 × 10−5*	0.025
	Left vs.Right SC-PUL					617	1.013	.311
	* Left vs. Right PUL-AMG					617	−9.785	4.070 × 10−21*
	Pathway × Head Motion	(1,616)	0.313	.576	5.090 × 10-4 *
	Hemisphere × Head Motion	(1,616)	0.055	.813	9.100 × 10-5 *
	Pathway × Hemisphere × Head Motion	(1,616)	0.332	.710	2.250 × 10-4 *
No Outliers Removed	* Pathway	(1,620)	32.416	2.194 × 10−8*	.049
	* Hemisphere	(1,620)	9.175	.003 *	.015
	* Pathway × Hemisphere	(1,620)	5.807	.016 *	.009
	Left vs. Right SC-PUL					621	0.654	.514
	* Left vs. Right PUL-AMG					621	−8.904	5.906 × 10−18*
	Pathway × Head Motion	(1,620)	0.030	.863	4.800 × 10−5
	Hemisphere × Head Motion	(1,620)	1.155	.283	.002
	Pathway × Hemisphere × Head Motion	(1,620)	0.332	.565	.001

*p <.05.