Table 1. Ten candidate causal variants, shared as caQTLs across all 10 populations.
GWAS information is from the GRASP database (Eicher et al., 2015). See Supplementary file 3 for all caQTL/GWAS overlaps.
| Chr | caQTL position | caQTL rsID | GWAS rsID | GWAS p-value | GWAS trait | Candidate gene |
|---|---|---|---|---|---|---|
| 15 | 86018746 | rs7161880 | rs4281668 | 9.90E-09 | Aggressive prostate cancer |
AKAP13 |
| 9 | 5097544 | rs3780372 | rs10974944 | 5.10E-32 | Myeloproliferative neoplasms | JAK2 |
| 12 | 111351439 | rs11065769 | rs10849917 | 3.21E-08 | Coronary artery disease | MYL2 |
| 2 | 68598955 | rs17035378 | rs17035378 | 8.00E-09 | Celiac disease | PLEK |
| 6 | 167433948 | rs6904946 | rs2301436 | 1.00E-12 | Crohn's disease | RNASET2 |
| 14 | 69273905 | rs194749 | rs194749 | 2.70E-10 | Inflammatory bowel disease | ZFP36L1 |
| 1 | 154359411 | rs9651053 | rs11265608 | 2.75E-08 | Juvenile idiopathic arthritis | IL6R |
| 4 | 1731653 | rs798764 | rs798766 | 3.90E-13 | Urinary bladder cancer |
FGFR3 |
| 13 | 40334852 | rs9603612 | rs9532434 | 4.52E-08 | Juvenile idiopathic arthritis | COG6 |
| 11 | 118560857 | rs73001406 | rs11216930 | 1.40E-09 | Glioma | PHLDB1 |