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. 2019 Jan 16;14(1):e0210070. doi: 10.1371/journal.pone.0210070

Table 2. Demographics and clinical characteristics of patients with oral premalignant lesions.

Characteristics OPLa samples (n = 83) No. (%)
Age at diagnosis. Mean (SDb) 60.8 (11.6)
Gender
Male 48 (57.8)
Female 35 (42.2)
Period of diagnosis
1995–1999 6 (7.2)
2000–2004 14 (16.9)
2005–2009 29 (34.9)
2010–2014 34(36.1)
Tobacco use
Non smoker 45 (54.2)
< 20 cigarettes/day 30 (36.1)
≥ 20 cigarettes/day 8 (9.6)
Alcohol consumption
Non drinker 58 (69.9)
< 100 grams/day 23 (27.7)
≥ 100 grams/day 2 (2.4)
Subsite
Gum 10 (12.0)
Cheek mucosa 35 (42.2)
Mobile tongue 22 (26.5)
Floor of the mouth 3 (3.6)
Oral cavity non-specified 9 (10.8)
Oropharynx 4 (4.8)
Previous neoplasia
Yes 7 (8.4)
No 76 (91.6)
Diagnostic
Oral lichen planus 45 (54.2)
Dysplasia low grade 13 (15.7)
Dysplasia moderate grade 12 (14.5)
Dysplasia severe grade 13 (15.7)
Treatment by diagnostic (n = 79)
Oral lichen planus 45 (54.2)
No treatment (clinical control) 13
Topical treatment 14
Surgery 14
CO2 laser 0
Combined treatment 1
Missing 3
Dysplasia low grade 13 (15.7)
No treatment (clinical control) 4
Topical treatment 1
Surgery 5
CO2 laser 1
Oral retinoid 0
Combined treatment 2
Dysplasia moderate grade 12 (14.5)
No treatment (clinical control) 3
Topical treatment 1
Surgery 8
CO2 laser 0
Oral retinoid 0
Dysplasia severe grade 13 (15.7)
No treatment (clinical control) 2
Topical treatment 0
Surgery 9
CO2 laser 0
Oral retinoid 0
Combined treatment 1
Missing 1

aOPL: Oral pre-malignant lesions.

bSD: Standard deviation.