Table 3.

Multivariable Cox regression (No. of patients included in the model = 159, No. of patients with EFS event = 24)

Variable	HR (95% CI)	P*
Age: ≥50 vs <50 y	1.37 (0.60 to 3.13)	.46
Histology grade: III vs I/II	1.21 (0.47 to 3.07)	.70
Estrogen receptor: positive vs negative	0.72 (0.30 to 1.73)	.46
Clinical stage: III vs II	1.89 (0.79 to 4.51)	.15
Chemotherapy: anthracycline-based vs not	0.52 (0.22 to 1.22)	.13
pCR: yes vs no	0.22 (0.08 to 0.61)	.004
Baseline TILs (10-unit increase)	0.75 (0.56 to 1.00)	.05

^*P values based on two-sided Wald tests from a multivariable Cox regression model including age, histology grade, estrogen receptor status, clinical stage, chemotherapy, pCR, and baseline TILs. CI= confidence interval; EFS = event-free survival; HR = hazard ratio; OR= odds ratio; pCR = pathologic complete response; TILs = tumor-infiltrating lymphocytes.