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. Author manuscript; available in PMC: 2020 Jan 15.
Published in final edited form as: Clin Cancer Res. 2018 Sep 4;25(2):573–583. doi: 10.1158/1078-0432.CCR-18-0655

Figure 2. Comparison of HeatITup with commonly used ITD detection algorithms.

Figure 2.

Comparative analysis of HeatITup with a) four commonly used methods on the capture-based WES TCGA AML cohort, where fill color represents the number of algorithms that identified a FLT3-ITD-positive individual; or b) a two-step CLIA-confirmed analysis workflow, consisting of a GATK/Pindel-based pipeline followed by manual variant review, on amplicon-based samples from the UPENN cohort.